Overview

  • Product name

    Anti-liver FABP antibody - N-terminal
    See all liver FABP primary antibodies
  • Description

    Rabbit polyclonal to liver FABP - N-terminal
  • Host species

    Rabbit
  • Specificity

    No cross reactivity with other proteins.
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human liver FABP aa 16-31 (N terminal).
    Sequence:

    EAFMKAIGLPEELIQK


    Database link: P07148

  • Positive control

    • Rat liver and kidney tissue lysates, HeLa, NREUO and SMMC cell lysates. Rat liver tissue and human liver cancer tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
    Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab190958 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.5 µg/ml.
IHC-P Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
  • Sequence similarities

    Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • Domain

    Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • FABP 1 antibody
    • FABP1 antibody
    • FABPL antibody
    • FABPL_HUMAN antibody
    • Fatty Acid Binding Protein 1 antibody
    • Fatty acid binding protein 1 liver antibody
    • Fatty Acid Binding Protein antibody
    • Fatty acid-binding protein 1 antibody
    • Fatty acid-binding protein antibody
    • Fatty acid-binding protein liver antibody
    • L FABP antibody
    • L-FABP antibody
    • liver antibody
    • Liver-type fatty acid-binding protein antibody
    see all

Images

  • All lanes : Anti-liver FABP antibody - N-terminal (ab190958) at 0.5 µg/ml

    Lane 1 : Rat liver lysate
    Lane 2 : Rat kidney lysate
    Lane 3 : HeLa lysate
    Lane 4 : NEURO lysate
    Lane 5 : SMMC lysate
  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat liver tissue tissue labeling liver FABP with ab190958 at 1 μg/ml.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human liver cancer tissue tissue labeling liver FABP with ab190958 at 1 μg/ml.

References

This product has been referenced in:

  • Zheng Z  et al. Hepatitis C virus mediated chronic inflammation and tumorigenesis in the humanised immune system and liver mouse model. PLoS One 12:e0184127 (2017). Read more (PubMed: 28886065) »
See 1 Publication for this product

Customer reviews and Q&As

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Human Tissue sections (Liver)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: Dako
Permeabilization
No
Specification
Liver
Fixative
Formaldehyde

Abcam user community

Verified customer

Submitted Jun 01 2016

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