Key features and details
- Rabbit polyclonal to LLGL1
- Suitable for: IHC-P
- Reacts with: Rat
- Isotype: IgG
Product nameAnti-LLGL1 antibody
See all LLGL1 primary antibodies
DescriptionRabbit polyclonal to LLGL1
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Rat
Predicted to work with: Mouse, Human
Synthetic peptide within Human LLGL1 aa 820-870 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: Q15334
- Rat brain tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 50% Glycerol, 0.01% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab203581 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.
(or 1/50 - 1/200 using a fluorescent secondary antibody).
FunctionCortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells.
Tissue specificityExpressed in brain, kidney, and muscle but is barely seen in heart and placenta. Down-regulated or lost in all cell lines and in most of the tumor samples analyzed. Loss was associated with advanced stage of the disease.
Sequence similaritiesBelongs to the WD repeat L(2)GL family.
Contains 14 WD repeats.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR (By similarity). Phosphorylated at least at Ser-663 by PRKCI.
Cellular localizationCytoplasm > cytoskeleton. Localized to the lateral membrane during the polarization and formation cell-cell contacts.
- Information by UniProt
- DLG4 antibody
- DLG4, formerly antibody
- Hugl 1 antibody
ab203581 has not yet been referenced specifically in any publications.