Overview

  • Product name

  • Description

    Rabbit polyclonal to LMX1b
  • Host species

    Rabbit
  • Specificity

    ab139736 is predicted to not cross-react with LMX1a.
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 17 amino acid synthetic peptide near the C terminus of Human LMX1b (NP_001167617).

  • Positive control

    • A-20 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab139736 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 42 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.
  • Tissue specificity

    Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets.
  • Involvement in disease

    Defects in LMX1B are the cause of nail-patella syndrome (NPS) [MIM:161200]; also known as onychoosteodysplasia. NPS is a disease that cause abnormal skeletal patterning and renal dysplasia.
  • Sequence similarities

    Contains 1 homeobox DNA-binding domain.
    Contains 2 LIM zinc-binding domains.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • LIM homeo box transcription factor 1 beta antibody
    • LIM homeobox transcription factor 1 beta antibody
    • LIM homeobox transcription factor 1-beta antibody
    • LIM-homeobox protein 1.2 antibody
    • LIM/homeobox protein 1.2 antibody
    • LIM/homeobox protein LMX1B antibody
    • LMX 1.2 antibody
    • LMX-1.2 antibody
    • LMX1.2 antibody
    • LMX1B antibody
    • LMX1B_HUMAN antibody
    • MGC138325 antibody
    • MGC142051 antibody
    • NPS 1 antibody
    • NPS1 antibody
    see all

Images

  • Immunohistochemistry (Formalin-fixed paraffin embedded sections) of mouse brain tissue labeling LMX1b with Anti-LMX1b antibody (ab139736) at 5μg/ml.
  • Immunohistochemical staining of human brain tissue with ab139736 at 5 µg/mL.

  • Lane 1 : Anti-LMX1b antibody (ab139736) at 1 µg/ml
    Lane 2 : Anti-LMX1b antibody (ab139736) at 2 µg/ml

    All lanes : A-20 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 42 kDa

  • Immunohistochemical staining of LMX1b in Human brain tissue with ab139736 at 20 ug/mL.

References

ab139736 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab139736.
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