Overview

  • Product name

    Loganin, ridoid glucoside
  • Description

    Antioxidant agent. Cytochrome P450 substrate.
  • Biological description

    Antioxidant agent. Cytochrome P450 substrate. Shows potent free-radical-scavenging activity. Selective β-secretase inhibitor. COX-1 inhibitor. Shows neuroprotective effects against Aβ(25-35)-induced and hydrogen peroxide-induced cell death. Shows immunostimulatory, hepatoprotective and neuroprotective effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    18524-94-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Babri S  et al. Effect of Acute Administration of loganin on Spatial Memory in Diabetic Male Rats. Adv Pharm Bull 3:91-5 (2013). Read more (PubMed: 24312818) »
  • Shi J  et al. Coumarin glycosides and iridoid glucosides with neuroprotective effects from Hydrangea paniculata. Planta Med 78:1844-50 (2012). Read more (PubMed: 23047248) »
  • Kwon SH  et al. Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells. Neurochem Int 58:533-41 (2011). Read more (PubMed: 21241762) »

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