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Lonidamine, Hexokinase inhibitor (ab142442)

  • Datasheet
  • SDS
  • COA
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Chemical Structure - Lonidamine, Hexokinase inhibitor (ab142442)

    Key features and details

    • Hexokinase inhibitor
    • CAS Number: 50264-69-2
    • Purity: > 98%
    • Soluble in ethanol to 10 mM and in DMSO to 100 mM
    • Form / State: Solid
    • Source: Synthetic

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    Overview

    • Product name

      Lonidamine, Hexokinase inhibitor
    • Description

      Hexokinase inhibitor
    • Alternative names

      • AF 1890
      • DICA
      • Diclondazolic acid
    • Purity

      > 98%
    • CAS Number

      50264-69-2
    • Chemical structure

      Chemical Structure

    Properties

    • Chemical name

      1-[(2,4-Dichlorophenyl)methyl]indazole-3-carboxylic acid
    • Molecular weight

      321.16
    • Molecular formula

      C15H10Cl2N2O2
    • PubChem identifier

      39562
    • Storage instructions

      Store at Room Temperature. The product can be stored for up to 12 months.
    • Solubility overview

      Soluble in ethanol to 10 mM and in DMSO to 100 mM
    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • SMILES

      C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)O
    • Source

      Synthetic

    • Research areas

      • Epigenetics and Nuclear Signaling
      • Transcription
      • Domain Families
      • Zinc Finger
      • Signal Transduction
      • Signaling Pathway
      • Nuclear Signaling
      • Nuclear Hormone Receptors
      • Estrogen
      • Signal Transduction
      • Signaling Pathway
      • Nuclear Signaling
      • Nuclear Hormone Receptors
      • Corticoid
      • Signal Transduction
      • Growth Factors/Hormones
      • Hormones
      • Neuroscience
      • Endocrine system
      • Thyroid axis
      • Neuroscience
      • Endocrine system
      • Gonadotrophic axis
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Corticoid
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Estrogen
      • Epigenetics and Nuclear Signaling
      • Transcription
      • Transcription Factors
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Orphan Nuclear Receptors
      • Signal Transduction
      • Metabolism
      • Drug metabolism
      • Cancer
      • Signal transduction
      • Nuclear signaling
      • Nuclear hormone receptors
      • Estrogen
      • Cancer
      • Signal transduction
      • Nuclear signaling
      • Nuclear hormone receptors
      • Other
      • Cancer
      • Tumor biomarkers
      • Receptors
      • Biochemicals
      • Chemical Type
      • Biochemicals
      • Metabolism
      • Pathways and Processes
      • Mitochondrial Metabolism
      • Mitochondrial Biogenesis
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Nucleotide metabolism
      • Molecular processes
      • Mitochondrial transcription
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Drug metabolism
      • Biochemicals
      • Pharmacology
      • Enzymes
      • Kinase
      • Hexokinase
      • Biochemicals
      • Pharmacology
      • Signaling
      • Immunomodulators
      • Antiparasitic

    Associated products

      Images

      • Chemical Structure - Lonidamine, Hexokinase inhibitor (ab142442)
        Chemical Structure - Lonidamine, Hexokinase inhibitor (ab142442)
        2D chemical structure image of ab142442, Lonidamine, Hexokinase inhibitor

      Protocols

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      Datasheets and documents

      • SDS download

      • Datasheet download

        Download
      • COA

      References (0)

      Publishing research using ab142442? Please let us know so that we can cite the reference in this datasheet.

      ab142442 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

      Show All Reviews Q&A
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      Question


      I want to dissolve 10 mg Lonidamin in 1 ml DMSo but it doesn't dissolves.

      What's your recommendation?

      Is it possible to sonicate it?

      Read More

      Abcam community

      Verified customer

      Asked on Aug 21 2013

      Answer

      The DMSO and HCl should not degrade/affect the quality of the Ionidamin.

      As some products may be difficult to solubilise, we recommend that rapid stirring, warming in a water bath, or sonication of the solution may help.

      Read More

      Jeremy Kasanov

      Abcam Scientific Support

      Answered on Aug 21 2013

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
      For licensing inquiries, please contact partnerships@abcam.com

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