Anti-LPA-2 antibody - C-terminal (ab198897)
Key features and details
- Rabbit polyclonal to LPA-2 - C-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-LPA-2 antibody - C-terminal
See all LPA-2 primary antibodies -
Description
Rabbit polyclonal to LPA-2 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to Human LPA-2 (C terminal). NP_004711.
Database link: Q9HBW0 -
Positive control
- Human gastric cancer tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab198897 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/25 - 1/100.
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Notes |
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IHC-P
1/25 - 1/100. |
Target
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Function
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. -
Tissue specificity
Expressed most abundantly in testes and peripheral blood leukocytes with less expression in pancreas, spleen, thymus and prostate. Little or no expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney, ovary, small intestine, or colon. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell surface. Cell membrane. Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA colocalizes with RALA in the endocytic vesicles. - Information by UniProt
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Database links
- Entrez Gene: 9170 Human
- Entrez Gene: 53978 Mouse
- Omim: 605110 Human
- SwissProt: Q9HBW0 Human
- SwissProt: Q9JL06 Mouse
- Unigene: 122575 Human
- Unigene: 23253 Mouse
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Alternative names
- EDG 4 antibody
- EDG-4 antibody
- EDG4 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab198897 has not yet been referenced specifically in any publications.