Overview

  • Product name

  • Description

    Rabbit polyclonal to LPA-3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human LPA-3 aa 165-259 (internal sequence).

  • Positive control

    • NT2D1 and PC3 whole cell lysates; Human testis tissue.
  • General notes

    Protein previously labeled as EDG7.

Properties

Applications

Our Abpromise guarantee covers the use of ab137497 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 40 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.
  • Tissue specificity

    Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Calcium mobilizing lysophosphatidic acid receptor LP A3 antibody
    • Calcium mobilizing lysophosphatidic acid receptor LPA 3 antibody
    • Calcium mobilizing lysophosphatidic acid receptor LPA3 antibody
    • EDG 7 antibody
    • Endothelial cell differentiation gene 7 antibody
    • Endothelial differentiation lysophosphatidic acid G protein coupled receptor 7 antibody
    • FLJ98231 antibody
    • GPCR antibody
    • HOFNH 30 antibody
    • HOFNH30 antibody
    • LP A3 antibody
    • LPA 3 antibody
    • LPA receptor 3 antibody
    • LPA receptor EDG 7 antibody
    • LPA receptor EDG7 antibody
    • LPA-3 antibody
    • LPA3 antibody
    • LPAR 3 antibody
    • Lpar3 antibody
    • LPAR3_HUMAN antibody
    • Lysophosphatidic acid receptor 3 antibody
    • Lysophosphatidic acid receptor Edg 7 antibody
    • Lysophosphatidic acid receptor Edg-7 antibody
    • Lysophosphatidic acid receptor Edg7 antibody
    • OTTHUMP00000011573 antibody
    • RP4 678I3 antibody
    • RP4678I3 antibody
    see all

Images

  • All lanes : Anti-LPA-3 antibody (ab137497) at 1/1000 dilution

    Lane 1 : NT2D1 whole cell lysate
    Lane 2 : PC3 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 40 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human testis tissue, labelling LPA-3 with ab137497 at 20 &microg/ml.

References

ab137497 has not yet been referenced specifically in any publications.

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