Anti-LPHN2 antibody (ab139498)
Key features and details
- Rabbit polyclonal to LPHN2
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-LPHN2 antibody
See all LPHN2 primary antibodies -
Description
Rabbit polyclonal to LPHN2 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
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Immunogen
Synthetic peptide corresponding to an internal region of Human LPHN2.
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Positive control
- Human prostate and vessel tissues; COS7 cells.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.88% Sodium chloride, 50% Glycerol, 49% PBS
without Mg2+ and Ca2+ -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab139498 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 10 µg/ml. | |
| ICC/IF | 1/100 - 1/500. |
Target
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Function
Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis. -
Tissue specificity
Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Contains 1 GPS domain.
Contains 1 olfactomedin-like domain.
Contains 1 SUEL-type lectin domain. -
Post-translational
modificationsProteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 23266 Human
- Entrez Gene: 99633 Mouse
- Entrez Gene: 171447 Rat
- Omim: 607018 Human
- SwissProt: O95490 Human
- SwissProt: Q8JZZ7 Mouse
- SwissProt: O88923 Rat
- Unigene: 24212 Human
see all -
Alternative names
- Adgrl2 antibody
- Adhesion G protein-coupled receptor L2 antibody
- AGRL2_HUMAN antibody
see all
Images
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Immunocytochemistry/ Immunofluorescence - Anti-LPHN2 antibody (ab139498)Immunofluorescence analysis of COS7 cells, labeling LPHN2, using ab139498 at a 1/100 dilution. The picture on the right is treated with the synthesized peptide.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LPHN2 antibody (ab139498)Immunohistochemistry analysis of paraffin-embedded, formalin-fixed Human vessel tissue, labeling LPHN2, using ab139498 at 10 µg/ml. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LPHN2 antibody (ab139498)Immunohistochemistry analysis of paraffin-embedded, formalin-fixed Human prostate tissue, labeling LPHN2, using ab139498 at 10 µg/ml.
Protocols
Datasheets and documents
References (0)
ab139498 has not yet been referenced specifically in any publications.
