Key features and details
- Rabbit polyclonal to LPHN2
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-LPHN2 antibody
See all LPHN2 primary antibodies
DescriptionRabbit polyclonal to LPHN2
Tested applicationsSuitable for: IHC-P, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to an internal region of Human LPHN2.
- Human prostate and vessel tissues; COS7 cells.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.88% Sodium chloride, 50% Glycerol, 49% PBS
without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab139498 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 10 µg/ml.|
|ICC/IF||1/100 - 1/500.|
FunctionCalcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis.
Tissue specificityExpressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others.
Sequence similaritiesBelongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Contains 1 GPS domain.
Contains 1 olfactomedin-like domain.
Contains 1 SUEL-type lectin domain.
modificationsProteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
- Information by UniProt
- Adgrl2 antibody
- Adhesion G protein-coupled receptor L2 antibody
- AGRL2_HUMAN antibody
Immunofluorescence analysis of COS7 cells, labeling LPHN2, using ab139498 at a 1/100 dilution. The picture on the right is treated with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded, formalin-fixed Human vessel tissue, labeling LPHN2, using ab139498 at 10 µg/ml.
Immunohistochemistry analysis of paraffin-embedded, formalin-fixed Human prostate tissue, labeling LPHN2, using ab139498 at 10 µg/ml.
ab139498 has not yet been referenced specifically in any publications.