Anti-LPHN2 antibody (ab139498)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-LPHN2 antibody
See all LPHN2 primary antibodies -
Description
Rabbit polyclonal to LPHN2 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
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Immunogen
Synthetic peptide corresponding to an internal region of Human LPHN2.
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Positive control
- Human prostate and vessel tissues; COS7 cells.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. -
Storage buffer
pH: 7,40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
Note: without Mg2+ and Ca2+ -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab139498 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 10 µg/ml. | |
| ICC/IF | 1/100 - 1/500. |
Target
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Function
Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis. -
Tissue specificity
Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Contains 1 GPS domain.
Contains 1 olfactomedin-like domain.
Contains 1 SUEL-type lectin domain. -
Post-translational
modificationsProteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 23266 Human
- Entrez Gene: 99633 Mouse
- Entrez Gene: 171447 Rat
- Omim: 607018 Human
- SwissProt: O95490 Human
- SwissProt: Q8JZZ7 Mouse
- SwissProt: O88923 Rat
- Unigene: 24212 Human
see all -
Alternative names
- Adgrl2 antibody
- Adhesion G protein-coupled receptor L2 antibody
- AGRL2_HUMAN antibody
see all
Images
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Immunocytochemistry/ Immunofluorescence - Anti-LPHN2 antibody (ab139498)Immunofluorescence analysis of COS7 cells, labeling LPHN2, using ab139498 at a 1/100 dilution. The picture on the right is treated with the synthesized peptide. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LPHN2 antibody (ab139498)Immunohistochemistry analysis of paraffin-embedded, formalin-fixed Human vessel tissue, labeling LPHN2, using ab139498 at 10 µg/ml. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LPHN2 antibody (ab139498)Immunohistochemistry analysis of paraffin-embedded, formalin-fixed Human prostate tissue, labeling LPHN2, using ab139498 at 10 µg/ml.
Datasheets and documents
References
ab139498 has not yet been referenced specifically in any publications.
