Anti-LPHN2 antibody - C-terminal (ab140830)
Key features and details
- Rabbit polyclonal to LPHN2 - C-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-LPHN2 antibody - C-terminal
See all LPHN2 primary antibodies -
Description
Rabbit polyclonal to LPHN2 - C-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Hamster, Cow, Turkey, Pig, Xenopus laevis, Monkey, Gorilla, Opossum, Common marmoset, Bat, Platypus, Elephant -
Immunogen
Synthetic peptide, corresponding to 16 amino acids from the C terminus of Human LPHN2 (NP_036434.1).
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Positive control
- Human brain (neurons and glia) tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140830 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 14 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 14 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis. -
Tissue specificity
Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Contains 1 GPS domain.
Contains 1 olfactomedin-like domain.
Contains 1 SUEL-type lectin domain. -
Post-translational
modificationsProteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 100405265 Common marmoset
- Entrez Gene: 281278 Cow
- Entrez Gene: 100052932 Horse
- Entrez Gene: 23266 Human
- Entrez Gene: 99633 Mouse
- Entrez Gene: 100013683 Opossum
- Entrez Gene: 100524685 Pig
- Entrez Gene: 100343149 Rabbit
see all -
Alternative names
- Adgrl2 antibody
- Adhesion G protein-coupled receptor L2 antibody
- AGRL2_HUMAN antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab140830 has not yet been referenced specifically in any publications.