Overview

  • Product name

  • Description

    Rabbit polyclonal to LRBA/BGL
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human LRBA/BGL aa 907-1038.

  • Positive control

    • Human rectum tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121765 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Contains 1 BEACH domain.
    Contains 6 WD repeats.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Cell membrane. Endoplasmic reticulum. Golgi apparatus > trans-Golgi network. Lysosome.
  • Information by UniProt
  • Database links

  • Alternative names

    • Beige-like protein antibody
    • BGL antibody
    • C80285 antibody
    • CDC4-like protein antibody
    • CDC4L antibody
    • CVID8 antibody
    • D3Ertd775e antibody
    • Lab300 antibody
    • LBA antibody
    • Lipopolysaccharide-responsive and beige-like anchor protein antibody
    • LPS-responsive vesicle trafficking beach and anchor containing antibody
    • Lrba antibody
    • LRBA_HUMAN antibody
    • Vesicle trafficking beach and anchor containing antibody
    see all

Images

  • ab121765 at 1/200 dilution staining LRBA/BGL in paraffin embedded Human rectum tissue by Immunohistochemistry.

References

This product has been referenced in:

  • Alangari A  et al. LPS-responsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency. J Allergy Clin Immunol 130:481-8.e2 (2012). Read more (PubMed: 22721650) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thank you for contacting us.

I assume, you are refering to ab22067, the mouse monoclonal antibody to LRBA?
Unfortunately,we are not carryingthis productanymore due to a change in the licensing agreement. We are very sorry about this inconvenience, but have no aliquot of the product available.

I am sorry to not have better news for you. Please do not hesitate to contact us if you need any more advice or information.

Read More

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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