Anti-LRFN4 antibody (ab106369)
Key features and details
- Rabbit polyclonal to LRFN4
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-LRFN4 antibody -
Description
Rabbit polyclonal to LRFN4 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to 14 aa from near the C-terminus of Human LRFN4 (Q6PJG9).
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Positive control
- Rat brain tissue lysate, Mouse brain tissue.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab106369 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF | Use a concentration of 20 µg/ml. | |
| IHC-P | Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol. | |
| WB | Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa. |
Target
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Function
Promotes neurite outgrowth in hippocampal neurons. May play a role in redistributing DLG4 to the cell periphery. -
Sequence similarities
Belongs to the LRFN family.
Contains 1 fibronectin type-III domain.
Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 7 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
Domain
The PDZ-binding motif is required for neurite outgrowth promotion (By similarity). This motif is also involved in DLG1-, DLG3- and DLG4-binding. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 78999 Human
- Entrez Gene: 225875 Mouse
- Entrez Gene: 688721 Rat
- Omim: 612810 Human
- SwissProt: Q6PJG9 Human
- SwissProt: Q80XU8 Mouse
- SwissProt: D4ABX8 Rat
- Unigene: 209979 Human
see all -
Alternative names
- fibronectin type III, immunoglobulin and leucine rich repeat domains 6 antibody
- FIGLER6 antibody
- leucine rich repeat and fibronectin type III domain containing 4 antibody
see all
Images
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Immunocytochemistry/ Immunofluorescence - Anti-LRFN4 antibody (ab106369)
Immunofluorescence of LRFN4 in mouse brain tissue with ab106369 at 20 ug/mL.
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Western blot - Anti-LRFN4 antibody (ab106369)Anti-LRFN4 antibody (ab106369) at 1 µg/ml + Rat brain tissue lysate at 15 µg
Predicted band size: 67 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LRFN4 antibody (ab106369)ab106369, at 2.5 ug/ml, staining LRFN4 in Mouse brain tissue by immunohistochemistry.
Protocols
Datasheets and documents
References (0)
ab106369 has not yet been referenced specifically in any publications.
