Overview

  • Product name
    Anti-LRFN4 antibody
  • Description
    Rabbit polyclonal to LRFN4
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to 14 aa from near the C-terminus of Human LRFN4 (Q6PJG9).

  • Positive control
    • Rat brain tissue lysate, Mouse brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab106369 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa.

Target

  • Function
    Promotes neurite outgrowth in hippocampal neurons. May play a role in redistributing DLG4 to the cell periphery.
  • Sequence similarities
    Belongs to the LRFN family.
    Contains 1 fibronectin type-III domain.
    Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 7 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Domain
    The PDZ-binding motif is required for neurite outgrowth promotion (By similarity). This motif is also involved in DLG1-, DLG3- and DLG4-binding.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • fibronectin type III, immunoglobulin and leucine rich repeat domains 6 antibody
    • FIGLER6 antibody
    • leucine rich repeat and fibronectin type III domain containing 4 antibody
    • Leucine-rich repeat and fibronectin type-III domain-containing protein 4 antibody
    • Lrfn4 antibody
    • LRFN4_HUMAN antibody
    • MGC3103 antibody
    • SALM3 antibody
    see all

Images

  • Immunocytochemistry/ Immunofluorescence - Anti-LRFN4 antibody (ab106369)
    Immunocytochemistry/ Immunofluorescence - Anti-LRFN4 antibody (ab106369)

    Immunofluorescence of LRFN4 in mouse brain tissue with ab106369 at 20 ug/mL.

  • Western blot - Anti-LRFN4 antibody (ab106369)
    Western blot - Anti-LRFN4 antibody (ab106369)
    Anti-LRFN4 antibody (ab106369) at 1 µg/ml + Rat brain tissue lysate at 15 µg

    Predicted band size: 67 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LRFN4 antibody (ab106369)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LRFN4 antibody (ab106369)
    ab106369, at 2.5 ug/ml, staining LRFN4 in Mouse brain tissue by immunohistochemistry.

References

ab106369 has not yet been referenced specifically in any publications.

Publishing research using ab106369? Please let us know so that we can cite the reference in this datasheet.

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