Key features and details
- Rabbit polyclonal to LRIG1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-LRIG1 antibody
DescriptionRabbit polyclonal to LRIG1
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human LRIG1. (Near the C terminal; NP_056356).
Database link: Q96JA1
- Human lung cancer tissue.
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab197985 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200.|
FunctionAct as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Tissue specificityWidely expressed.
Sequence similaritiesContains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
DomainThe LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted.
- Information by UniProt
- Leucine rich repeat protein antibody
- Leucine rich repeat protein LRIG1 antibody
- leucine rich repeats and immunoglobulin like domains 1 antibody
ab197985 has been referenced in 1 publication.
- Yang B et al. Lrig1 is a positive prognostic marker in hepatocellular carcinoma. Onco Targets Ther 9:7071-7079 (2016). IHC-P ; Human . PubMed: 27895499