Overview

  • Product name

    Anti-LRIG3 antibody [LRG3-3]
    See all LRIG3 primary antibodies
  • Description

    Mouse monoclonal [LRG3-3] to LRIG3
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Monkey
  • Immunogen

    Synthetic peptide corresponding to Human LRIG3 aa 65-82 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Sequence:

    LARLPEPLPSWVARLDLS


    Database link: Q6UXM1

  • Positive control

    • U87 cells; H1395 cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab213960 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 123 kDa.
ICC/IF Use a concentration of 5 µg/ml.

Target

  • Function

    May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1.
  • Tissue specificity

    Widely expressed.
  • Sequence similarities

    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 15 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Cellular localization

    Cell membrane. Cytoplasmic vesicle membrane. Detected in cytoplasmic vesicles when coexpressed with ERBB4.
  • Information by UniProt
  • Database links

  • Alternative names

    • Leucine-rich repeats and immunoglobulin-like domains protein 3 antibody
    • Leucine-rich repeats- and immunoglobulin-like domains- containing protein 3 antibody
    • LIG-3 antibody
    • LIG3 antibody
    • LRIG1-3 antibody
    • Lrig3 antibody
    • LRIG3_HUMAN antibody
    see all

Images

  • Immunofluorescent analysis of U87 cells (4% paraformaldehyde fixed, 0.5% Triton X-100 permealized) labeling LRIG3 with ab213960 at 5 μg/ml dilution, followed by Goat Anti-Mouse IgG, Cy3 conjugate secondary detection (red). Cells were counterstained with DAPI (blue) to stain nuclei.

  • All lanes : Anti-LRIG3 antibody [LRG3-3] (ab213960)

    Lane 1 : H1395 cell extract
    Lane 2 : H1395 cell extract with LRIG3 immunizing peptide (Human, 65-82)

    Lysates/proteins at 2 µg/ml per lane.

    Secondary
    All lanes : Goat Anti-Mouse IgG-Peroxidase

    Developed using the ECL technique.

    Predicted band size: 123 kDa

References

ab213960 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab213960.
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