Overview

  • Product name

    Anti-LRPAP1 antibody [EPR3328]
    See all LRPAP1 primary antibodies
  • Description

    Rabbit monoclonal [EPR3328] to LRPAP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, IPmore details
    Unsuitable for: Flow Cyt or ICC
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human LRPAP1 (UniProt ID: P30533).

  • Positive control

    • Human fetal kidney, 293T, A549, BxPC3 and NCCIT lysates; Human brain and kidney tissues
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab133488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt or ICC.
  • Target

    • Function

      Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
    • Involvement in disease

      Note=In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.
    • Sequence similarities

      Belongs to the alpha-2-MRAP family.
    • Post-translational
      modifications

      N-glycosylated.
    • Cellular localization

      Endoplasmic reticulum. Cytoplasm. Cell surface. Intracellular and associated with cell surface receptors. Found in the endoplasmic reticulum.
    • Information by UniProt
    • Database links

    • Alternative names

      • 39 kDa receptor-associated protein antibody
      • A2MRAP antibody
      • A2RAP antibody
      • Alpha 2 macroglobulin receptor associated protein antibody
      • Alpha 2 MRAP antibody
      • Alpha-2-macroglobulin receptor-associated protein antibody
      • Alpha-2-MRAP antibody
      • AMRP_HUMAN antibody
      • HBP44 antibody
      • Lipoprotein receptor associated protein antibody
      • Low density lipoprotein receptor related protein associated protein 1 antibody
      • Low density lipoprotein receptor-related protein-associated protein 1 antibody
      • Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein antibody
      • Low density lipoprotein related protein associated protein 1 antibody
      • low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) antibody
      • Lrpap1 antibody
      • MGC138272 antibody
      • MRAP antibody
      • MYP23 antibody
      • RAP antibody
      see all

    Images

    • All lanes : Anti-LRPAP1 antibody [EPR3328] (ab133488) at 1/1000 dilution

      Lane 1 : Human fetal kidney lysate
      Lane 2 : 293T lysate
      Lane 3 : A549 lysate
      Lane 4 : BxPC3 lysate
      Lane 5 : NCCIT lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 41 kDa

    • Immunohistochemical analysis of LRPAP1 in paraffin embedded Human kidney tissue, using ab133488 at a 1/50 dilution.
    • Immunohistochemical analysis of LRPAP1 in paraffin embedded Human brain tissue, using ab133488 at a 1/50 dilution.

    References

    ab133488 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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