Key features and details
- Rabbit polyclonal to LRR-1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-LRR-1 antibody
See all LRR-1 primary antibodies
DescriptionRabbit polyclonal to LRR-1
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
- WB: Human fetal brain lysate and NIH-3T3 cell lysate; IHC: Human pancreas cancer tissue.
Previously labelled as PPIL5.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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FormLyophilized:Reconstitute in 200ul sterile water
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab169947 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 47 kDa).|
|IHC-P||1/100 - 1/500.|
FunctionMay negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Tissue specificityUbiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney.
PathwayProtein modification; protein ubiquitination.
Sequence similaritiesContains 7 LRR (leucine-rich) repeats.
- Information by UniProt
- 4 1BB mediated signaling molecule antibody
- 4 1BBlrr antibody
- 4-1BB-mediated-signaling molecule antibody
ab169947 has not yet been referenced specifically in any publications.