Overview

  • Product name

  • Description

    Rabbit polyclonal to LRRFIP1
  • Host species

    Rabbit
  • Specificity

    ab133218 is predicted to not cross-react with other LRRFIP family members. Three isoforms of LRRFIP1 are known to exist; ab133218 will only recognize the two longer isoforms.
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide from the C terminal of Human LRRFIP1

  • Positive control

    • Human prostate tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab133218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 89 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA.
  • Tissue specificity

    Ubiquitously expressed.
  • Sequence similarities

    Belongs to the LRRFIP family.
  • Developmental stage

    Widely expressed in fetal tissues.
  • Cellular localization

    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLAP 1 antibody
    • FLAP1 antibody
    • FLIIAP 1 antibody
    • FLIIAP1 antibody
    • GC binding factor 2 antibody
    • GC-binding factor 2 antibody
    • GCF 2 antibody
    • GCF2 antibody
    • HUFI 1 antibody
    • HUFI1 antibody
    • Leucine rich repeat (in FLII) interacting protein 1 antibody
    • Leucine rich repeat flightless interacting protein 1 antibody
    • Leucine-rich repeat flightless-interacting protein 1 antibody
    • LRR FLII interacting protein 1 antibody
    • LRR FLII-interacting protein 1 antibody
    • LRRF1_HUMAN antibody
    • LRRFIP 1 antibody
    • Lrrfip1 antibody
    • MGC10947 antibody
    • MGC119738 antibody
    • MGC119739 antibody
    • NEDD8 conjugating enzyme antibody
    • TAR RNA interacting protein antibody
    • TAR RNA-interacting protein antibody
    • Transcription factor 9 like antibody
    • TRIP antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin embedded Human prostate tissue labelling LRRFIP1 with ab133218 at 5µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab133218 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab133218.
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