Overview

  • Product name

  • Description

    Rabbit polyclonal to LRRTM2
  • Host species

    Rabbit
  • Specificity

    ab106627 is predicted not to cross-react with other LRRTM family members.
  • Tested applications

    Suitable for: ICC/IF, ICC, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 17 amino acid synthetic peptide from near the C terminus of Human LRRTM2 (EAW62125).

  • Positive control

    • SK-N-SH cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
ICC Use a concentration of 2.5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 59 kDa.
IHC-P Use a concentration of 2.5 µg/ml.

Target

  • Function

    Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.
  • Tissue specificity

    Expressed in neuronal tissues.
  • Sequence similarities

    Belongs to the LRRTM family.
    Contains 10 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Domain

    Synaptogenic effects are mediated by the extracellular LRR region.
  • Cellular localization

    Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Localized to excitatory synapses.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ76283 antibody
    • FLJ99831 antibody
    • KIAA0416 antibody
    • Leucine rich repeat transmembrane neuronal 2 antibody
    • Leucine rich repeat transmembrane neuronal 2 protein antibody
    • Leucine rich repeat transmembrane protein 2 antibody
    • Leucine-rich repeat neuronal 2 protein antibody
    • Leucine-rich repeat transmembrane neuronal protein 2 antibody
    • LRRN2 antibody
    • LRRT2_HUMAN antibody
    • Lrrtm2 antibody
    see all

Images

  • All lanes : Anti-LRRTM2 antibody (ab106627) at 1 µg/ml

    Lane 1 : SK-N-SH cell lysate
    Lane 2 : SK-N-SH cell lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 59 kDa

  • Immunofluorescence of LRRTM2 in Human brain tissue with ab106627 at 20 ug/mL.
  • Immunohistochemistry of LRRTM2 in human brain tissue with ab106627 at 2.5 µg/ml.

References

ab106627 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab106627.
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