Key features and details
- Rabbit polyclonal to LRRTM2
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-LRRTM2 antibody
See all LRRTM2 primary antibodies
DescriptionRabbit polyclonal to LRRTM2
Specificityab106627 is predicted not to cross-react with other LRRTM family members.
Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
A 17 amino acid synthetic peptide from near the C terminus of Human LRRTM2 (EAW62125).
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106627 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 59 kDa.|
|IHC-P||Use a concentration of 2.5 µg/ml.|
FunctionInvolved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.
Tissue specificityExpressed in neuronal tissues.
Sequence similaritiesBelongs to the LRRTM family.
Contains 10 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
DomainSynaptogenic effects are mediated by the extracellular LRR region.
Cellular localizationCell membrane. Cell junction > synapse > postsynaptic cell membrane. Localized to excitatory synapses.
- Information by UniProt
- FLJ76283 antibody
- FLJ99831 antibody
- KIAA0416 antibody
All lanes : Anti-LRRTM2 antibody (ab106627) at 1 µg/ml
Lane 1 : SK-N-SH cell lysate
Lane 2 : SK-N-SH cell lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 59 kDa
Immunofluorescence of LRRTM2 in Human brain tissue with ab106627 at 20 ug/mL.
Immunohistochemistry of LRRTM2 in human brain tissue with ab106627 at 2.5 µg/ml.
ab106627 has not yet been referenced specifically in any publications.