Overview

  • Product name

    Anti-LSM1 antibody - C-terminal
    See all LSM1 primary antibodies
  • Description

    Rabbit polyclonal to LSM1 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IPmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human LSM1 (C terminal). The exact sequence is proprietary. Conjugated to a protein carrier.
    Database link: O15116

  • Positive control

    • WB: Jurkat, Raji, NCI-H929, HEK-293T and A431 whole cell extracts. IP: HEK-293T whole cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab229311 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 15 kDa.
IP 1/100 - 1/1000.

Target

  • Function

    Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3'-terminal U-tract of U6 snRNA.
  • Tissue specificity

    Has elevated expression in pancreatic cancer and in several cancer-derived cell lines.
  • Sequence similarities

    Belongs to the snRNP Sm proteins family.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cancer associated Sm like protein antibody
    • Cancer associated Sm-like antibody
    • Cancer-associated Sm-like antibody
    • CASM antibody
    • lsm1 antibody
    • LSM1 antibody antibody
    • LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) antibody
    • Lsm1 protein antibody
    • LSM1, U6 small nuclear RNA associated antibody
    • LSM1_HUMAN antibody
    • Small nuclear ribonuclear CaSm antibody
    • U6 snRNA associated Sm-like protein LSm1 antibody
    • U6 snRNA-associated Sm-like protein LSm1 antibody
    • YJL124C antibody
    see all

Images

  • All lanes : Anti-LSM1 antibody - C-terminal (ab229311) at 1/1000 dilution

    Lane 1 : Jurkat (Human T cell leukemia cell line from peripheral blood) whole cell extracts
    Lane 2 : Raji (Human Burkitt's lymphoma cell line) whole cell extracts
    Lane 3 : NCI-H929 whole cell extracts
    Lane 4 : HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extracts
    Lane 5 : A431 (Human epidermoid carcinoma cell line) whole cell extracts

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 15 kDa



    15% SDS-PAGE

  • LSM1 was immunoprecipitated from HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extract with 5 µg ab229311. Western blot was performed from the immunoprecipitate using ab229311.

    Lane 1: HEK-293T whole cell extract (Input).

    Lane 2: Control IgG IP in HEK-293T whole cell extract.

    Lane 3: ab229311 IP in HEK-293T whole cell extract.

     

     

References

ab229311 has not yet been referenced specifically in any publications.

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