Overview

  • Product name
    Anti-LSP1 antibody
    See all LSP1 primary antibodies
  • Description
    Rabbit polyclonal to LSP1
  • Host species
    Rabbit
  • Specificity
    This epitope affinity purified rabbit polyclonal antibody reacts predominantly with LSP1. By immunoblot analysis, a ~52 kDa immunoreactive protein from Mouse Spleen tissue lysate was detected (sample were boiled prior to subject 10% SDSpolyacrylamide gel electrophoresis). This band is abolished by the depletion of the synthetic immunizing peptide.
  • Tested applications
    Suitable for: ELISA, IP, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide:

    KLARQASIELP

    , corresponding to amino acids 246-256 of Human LSP1.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

Properties

Applications

Our Abpromise guarantee covers the use of ab21637 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.1 - 1 µg/ml.
IP Use 3µg for 105 cells.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 52 kDa.

Target

  • Function
    May play a role in mediating neutrophil activation and chemotaxis.
  • Tissue specificity
    Activated T-lymphocytes.
  • Post-translational
    modifications
    Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • 47 kDa actin binding protein antibody
      • 47 kDa actin-binding protein antibody
      • 52 kDa phosphoprotein antibody
      • F actin binding and cytoskeleton associated protein antibody
      • Leufactin (leukocyte F-actin binding protein) antibody
      • Leufactin antibody
      • Leukocyte F actin binding protein antibody
      • Leukocyte specific protein 1 antibody
      • LSP 1 antibody
      • Lsp1 antibody
      • LSP1_HUMAN antibody
      • Lymphocyte specific antigen WP34 antibody
      • Lymphocyte specific protein 1 antibody
      • Lymphocyte specific protein pp52 antibody
      • Lymphocyte-specific antigen WP34 antibody
      • Lymphocyte-specific protein 1 antibody
      • OTTHUMP00000014138 antibody
      • OTTHUMP00000014139 antibody
      • OTTHUMP00000014140 antibody
      • OTTHUMP00000069612 antibody
      • OTTHUMP00000069614 antibody
      • OTTHUMP00000069615 antibody
      • OTTHUMP00000069616 antibody
      • pp52 antibody
      • Protein pp52 antibody
      • S37 protein antibody
      • WP 34 antibody
      • WP34 antibody
      see all

    References

    This product has been referenced in:
    • Wu JL  et al. Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells. Nat Commun 7:12526 (2016). Read more (PubMed: 27555448) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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