Overview

  • Product name

    Anti-LTBP4 antibody
  • Description

    Rabbit polyclonal to LTBP4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human LTBP4 aa 977-1180.
    Database link: Q8N2S1

  • Positive control

    • IHC-P: Human kidney tissue. ICC/IF: HepG2 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab222844 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/200.
IHC-P 1/20 - 1/200.

Target

  • Function

    May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).
  • Tissue specificity

    Highly expressed in heart, skeletal muscle, pancreas, uterus, and small intestine. Weakly expressed in placenta and lung.
  • Involvement in disease

    Urban-Rifkin-Davis syndrome
  • Sequence similarities

    Belongs to the LTBP family.
    Contains 16 EGF-like domains.
    Contains 4 TB (TGF-beta binding) domains.
  • Developmental stage

    Very low expression in fetal brain, liver, heart, spleen and thymus.
  • Post-translational
    modifications

    Contains hydroxylated asparagine residues.
  • Cellular localization

    Secreted, extracellular space, extracellular matrix.
  • Information by UniProt
  • Database links

  • Alternative names

    • latent transforming growth factor beta binding protein 4 antibody
    • latent transforming growth factor beta binding protein 4L antibody
    • Latent-transforming growth factor beta-binding protein 4 antibody
    • LTBP 4 antibody
    • LTBP-4 antibody
    • LTBP4 antibody
    • LTBP4_HUMAN antibody
    • LTBP4L antibody
    • LTBP4S antibody
    see all

Images

  • HepG2 (human liver hepatocellular carcinoma cell line) cells stained for LTBP4 (green) using ab222844 at 1/100 dilution in ICC/IF. Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L) was used as secondary antibody.

  • Paraffin-embedded human kidney tissue stained for LTBP4 using ab222844 at 1/100 dilution in immunohistochemical analysis.

References

ab222844 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab222844.
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