Anti-LTBR antibody [3C8] - Low endotoxin, Azide free (ab171241)
- Datasheet
- References
- Protocols
Overview
-
Product nameAnti-LTBR antibody [3C8] - Low endotoxin, Azide free
See all LTBR primary antibodies -
DescriptionRat monoclonal [3C8] to LTBR - Low endotoxin, Azide free
-
Host speciesRat
-
Tested applicationsSuitable for: Functional Studies, Flow Cytmore details
-
Species reactivityReacts with: Mouse
-
Immunogen
The details of the immunogen for this antibody are not available.
-
Positive control
- NIH/3T3 cells.
-
General notes
Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.
Properties
-
FormLiquid
-
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Storage bufferpH: 7.20
Constituent: 100% PBS -
Concentration information loading... -
PurityProtein G purified
-
ClonalityMonoclonal
-
Clone number3C8
-
IsotypeIgG1
-
Light chain typekappa
-
Research areas
Associated products
-
Compatible Secondaries
-
Conjugation kits
-
Positive Controls
Applications
Our Abpromise guarantee covers the use of ab171241 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Functional Studies | Use at an assay dependent concentration. ab171241 is reported to have agonistic activity (via activation of NKκ B). |
|
| Flow Cyt | Use at an assay dependent concentration. ab171241 can be used at less than or equal to 0.5μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10e5 to 10e8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Target
-
FunctionReceptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
-
Sequence similaritiesContains 4 TNFR-Cys repeats.
-
Cellular localizationMembrane.
- Information by UniProt
-
Database links
- Entrez Gene: 17000 Mouse
- SwissProt: P50284 Mouse
- Unigene: 3122 Mouse
-
Alternative names
- CD18 antibody
- D12S370 antibody
- LT beta R antibody
see all
Images
-
![Flow Cytometry - Anti-LTBR antibody [3C8] - Low endotoxin, Azide free (ab171241)](https://www.abcam.com/ps/products/171/ab171241/Images/ab171241-172451-ab171241.JPG)
Flow Cytometry - Anti-LTBR antibody [3C8] - Low endotoxin, Azide free (ab171241)Flow cytometry analysis of total viable NIH/3T3 cells (10e5 to 10e8) labeling LTBR with ab171241 (filled histogram) at 0.25µg or Rat IgG1 control (open histogram). Followed by anti-Rat IgG Biotin and Streptavidin PE.
Datasheets and documents
Protocols
References
ab171241 has not yet been referenced specifically in any publications.
