Overview

  • Product name

  • Description

    Rabbit polyclonal to LTBR
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IP, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide within Human LTBR aa 385-435. The exact sequence is proprietary.
    Database link: P36941

  • Positive control

    • WB: HeLa, HEK-293T and Jurkat whole cell lysates. IP: HeLa whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab226377 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
WB 1/1000 - 1/5000. Predicted molecular weight: 47 kDa.

Target

  • Function

    Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
  • Sequence similarities

    Contains 4 TNFR-Cys repeats.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD18 antibody
    • D12S370 antibody
    • LT beta R antibody
    • LTBETAR antibody
    • Ltbr antibody
    • Lymphotoxin B receptor antibody
    • Lymphotoxin beta receptor (TNFR superfamily, member 3) antibody
    • Lymphotoxin beta receptor antibody
    • Lymphotoxin-beta receptor antibody
    • TNF R III antibody
    • TNF-RIII antibody
    • TNFCR antibody
    • TNFR RP antibody
    • TNFR superfamily member 3 antibody
    • TNFR-III antibody
    • TNFR2 RP antibody
    • TNFR2RP antibody
    • TNFR3 antibody
    • TNFRII antibody
    • TNFRRP antibody
    • TNFRSF 3 antibody
    • TNFRSF3 antibody
    • TNR3_HUMAN antibody
    • Tumor necrosis factor C receptor antibody
    • Tumor necrosis factor receptor 2 related protein antibody
    • Tumor necrosis factor receptor 2-related protein antibody
    • Tumor necrosis factor receptor superfamily member 3 antibody
    • Tumor necrosis factor receptor superfamily member 3 precursor antibody
    • Tumor necrosis factor receptor type III antibody
    see all

Images

  • All lanes : Anti-LTBR antibody (ab226377) at 0.1 µg/ml

    Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
    Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
    Lane 3 : Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate

    Lysates/proteins at 50 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 47 kDa


    Exposure time: 30 seconds


    Lysates prepared using NETN lysis buffer.

  • LTBR was immunoprecipitated from HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate (prepared using NETN lysis buffer; 1 mg for IP, 20% of IP loaded) with ab226377 at 6 µg/mg lysate. Western blot was performed from the immunoprecipitate using ab226377 at 0.4 µg/ml.

    Lane 1: ab226377 IP in HeLa whole cell lysate.

    Lane 2: Control IgG IP in HeLa whole cell lysate.

    Detection:  Chemiluminescence with exposure time of 30 seconds.

References

ab226377 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab226377.
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