Key features and details
- Rabbit polyclonal to LTBR
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab70063 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 48 kDa).|
|ICC/IF||1/500 - 1/1000.|
FunctionReceptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
Sequence similaritiesContains 4 TNFR-Cys repeats.
- Information by UniProt
- CD18 antibody
- D12S370 antibody
- LT beta R antibody
All lanes : Anti-LTBR antibody (ab70063) at 1/500 dilution
Lane 1 : HeLa cell extract
Lane 2 : HepG2 cell extract
Lane 3 : HeLa cell extract with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 48 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted?
Additional bands at: 22 kDa. We are unsure as to the identity of these extra bands.
HeLa cells with ab70063 at 1/500 dilution, with and without the immunising peptide.
ab70063 has been referenced in 1 publication.
- Shen M et al. Lymphotoxin ß receptor activation promotes bladder cancer in a nuclear factor-?B-dependent manner. Mol Med Rep 11:783-90 (2015). IHC-P ; Human . PubMed: 25369740