Overview

  • Product name

    Anti-Luteinizing Hormone alpha antibody [LHa/756]
  • Description

    Mouse monoclonal [LHa/756] to Luteinizing Hormone alpha
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human Luteinizing Hormone alpha.
    Database link: P01215

  • Positive control

    • Human pituitary tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab219296 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 1 - 2 µg/ml. Do not perform antigen retrieval.

Target

  • Relevance

    The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Luteinizing hormone (LH) is a hormone synthesized and secreted by gonadotropes in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle stimulating hormone (FSH) it is necessary for proper reproductive function. In the female, an acute rise of LH triggers ovulation. In the male, where LH had also been called Interstitial Cell Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • CGA antibody
    • LHA antibody
    • LSH alpha antibody
    • Luteinizing hormone alpha chain antibody

Images

  • Immunohistochemical analysis of paraffin embedded, formalin fixed Human pituitary tissue labeling Luteinizing Hormone alpha using ab219296 at 2 µg/ml

References

ab219296 has not yet been referenced specifically in any publications.

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