Overview

  • Product name

  • Description

    Rabbit polyclonal to LXN/TCI
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human LXN/TCI (internal sequence) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: Q9BS40

  • Positive control

    • Human spleen tissue. Human prostate carcinoma tissue. 293 cell lysate. WiDr cells.
  • General notes

    Protein previously labeled as LXN.

Properties

Applications

Our Abpromise guarantee covers the use of ab188793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 26 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Flow Cyt 1/10 - 1/50.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

Target

  • Function

    Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4.
  • Tissue specificity

    Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.
  • Sequence similarities

    Belongs to the protease inhibitor I47 (latexin) family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • ECI antibody
    • Endogenous carboxypeptidase inhibitor antibody
    • Latexin antibody
    • Latexin protein antibody
    • LXN antibody
    • LXN_HUMAN antibody
    • MUM antibody
    • Protein MUM antibody
    • TCI antibody
    • Tissue carboxypeptidase inhibitor antibody
    see all

Images

  • All lanes : Anti-LXN/TCI antibody (ab188793) at 1/1000 dilution

    Lane 1 : Non transfected 293 cells
    Lane 2 : 293 cells transiently transfected with the LXN/TCI gene

    Lysates/proteins at 2 µg per lane.

    Predicted band size: 26 kDa

  • Immunohistochemistry analysis of formalin/PFA-fixed paraffin-embedded human spleen sections labeling LXN/TCI using ab188793 at 10 µg/ml.

  • Immunohistochemistry analysis of formalin/PFA-fixed paraffin-embedded human spleen sections labeling LXN/TCI using ab188793 at 10 µg/ml.

  • Immunohistochemistry analysis of formalin/PFA-fixed paraffin-embedded human prostate carcinoma sections labeling LXN/TCI using ab188793 at 10 µg/ml.

  • Flow cytometry of WiDr cells using ab188793 at a 1/10 dilution (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References

ab188793 has not yet been referenced specifically in any publications.

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