Recombinant Anti-LXR alpha antibody [EPR6508(N)] - BSA and Azide free (ab190727)


  • Product name
    Anti-LXR alpha antibody [EPR6508(N)] - BSA and Azide free
    See all LXR alpha primary antibodies
  • Description
    Rabbit monoclonal [EPR6508(N)] to LXR alpha - BSA and Azide free
  • Host species
  • Tested applications
    Suitable for: Flow Cyt, WB, ICC/IFmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Sheep, Human
  • Immunogen

    Synthetic peptide within Human LXR alpha aa 50-150 (Cysteine residue). The exact sequence is proprietary.
    Database link: Q13133

  • Positive control
    • Human fetal liver, Jurkat and MCF-7 cell lysates. Jurkat cells and MCF7 cells.
  • General notes

    The formulation and the concentration of this product is compatible for metal-conjugation for mass cytometry (CyTOF®).

    Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.


Our Abpromise guarantee covers the use of ab190727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

ab199376 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

WB Use at an assay dependent concentration. Predicted molecular weight: 50 kDa.

Can be blocked with LXR alpha peptide (ab191835).

ICC/IF Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function
      Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
    • Tissue specificity
      Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.
    • Sequence similarities
      Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • Cellular localization
    • Information by UniProt
    • Database links
    • Alternative names
      • Liver X receptor alpha antibody
      • LXR a antibody
      • LXRA antibody
      • NR1H3 antibody
      • NR1H3_HUMAN antibody
      • Nuclear receptor subfamily 1 group H member 3 antibody
      • Oxysterols receptor LXR alpha antibody
      • Oxysterols receptor LXR-alpha antibody
      • RLD 1 antibody
      • RLD1 antibody
      see all


    • Flow cytometric analysis of permeabilized MCF-7 cells labeling LXR alpha using ab176323 at a 1/10 dilution (red) or a rabbit IgG control (green).

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab176323).

    • Immunofluorescent staining of Jurkat cells labeling LRX alpha using ab176323 at a 1/50 dilution.

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab176323).


    ab190727 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab190727.
    Please use the links above to contact us or submit feedback about this product.

    For licensing inquiries, please contact

    Sign up