Overview

  • Product name

    Anti-LXR beta/NER antibody
    See all LXR beta/NER primary antibodies
  • Description

    Rabbit polyclonal to LXR beta/NER
  • Host species

    Rabbit
  • Specificity

    ab106473 is predicted not to cross-react with LXR alpha.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human LXR beta/NER (N terminal).
    Database link: P55055

  • Positive control

    • Human lung tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106473 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 51 kDa.

Target

  • Function

    Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Liver X nuclear receptor beta antibody
    • Liver X receptor beta antibody
    • LX receptor beta antibody
    • LXR b antibody
    • LXR beta antibody
    • LXRB antibody
    • NER antibody
    • NER I antibody
    • NER1 antibody
    • NR1H 2 antibody
    • NR1H2 antibody
    • NR1H2_HUMAN antibody
    • Nuclear orphan receptor LXR beta antibody
    • Nuclear receptor NER antibody
    • Nuclear receptor subfamily 1 group H member 2 antibody
    • OR-1 antibody
    • Oxysterols receptor LXR-beta antibody
    • RIP15 antibody
    • Steroid hormone nuclear receptor NER antibody
    • Ubiquitously-expressed nuclear receptor antibody
    • UNR antibody
    see all

Images

  • Lane 1 : Anti-LXR beta/NER antibody (ab106473) at 1 µg/ml
    Lane 2 : Anti-LXR beta/NER antibody (ab106473) at 2 µg/ml

    All lanes : Human Lung Tissue Lysate


    Lysates/proteins at 15 µg per lane.

    Predicted band size: 51 kDa

References

This product has been referenced in:

  • Courtaut F  et al. Liver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRß subcellular localization. Oncotarget 6:26651-62 (2015). IF . Read more (PubMed: 26450852) »
  • Gabitova L  et al. Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR. Cell Rep 12:1927-38 (2015). Read more (PubMed: 26344763) »
See all 3 Publications for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Application
Western blot
Sample
Human Cell lysate - whole cell (A431 cells)
Gel Running Conditions
Reduced Denaturing
Loading amount
25 µg
Specification
A431 cells
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 22°C

Abcam user community

Verified customer

Submitted Nov 18 2015

Answer

Thank you for your enquiry and your interest in our products.

We have several antibodies against LXR beta (ab24361, ab56237, ab58089, ab58092, ab76983, ab106473) . The tested application/species/unit size can be found on the on-line product datasheets. I would advise you to take a look at these document to see which product would suit you need best.

If you need any further assistance in the future, please do not hesitate to contact me.

Regarding shipment and packaging information, could you please contact our authorized distributor in India for further details.

NuLife Consultants & Distributors (Pvt.) Ltd.
NuLife Consultants & Distributors (Pvt.) Ltd.
M-52, First Floor,
Lajpat Nagar- Part-II,
New Delhi-110024-India
Tel 011-46112691/ 46112692/ 29836141

Website http://www.nulife.in/

Fax 91 - 011-46586216 Email mailto:nulife@bol.net.inand mailto:sales@nulife.in

I hope this helps and if I can assist further, please do not hesitate to contact me.

Read More

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up