• Product name
    Anti-LXR beta/NER antibody
    See all LXR beta/NER primary antibodies
  • Description
    Goat polyclonal to LXR beta/NER
  • Host species
  • Specificity
    Based on the peptide used, this antibody is expected to be specific for LXR beta/NER and not to cross-react with LXR alpha.
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog
  • Immunogen

    Synthetic peptide corresponding to Human LXR beta/NER aa 2-14 (N terminal).


  • Positive control
    • Lysate prepared from human bone marrow. Human spleen tissue.



Our Abpromise guarantee covers the use of ab24361 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 60, 80 kDa (predicted molecular weight: 51 kDa).
IHC-P Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.


  • Function
    Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
  • Tissue specificity
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • Liver X nuclear receptor beta antibody
    • Liver X receptor beta antibody
    • LX receptor beta antibody
    • LXR b antibody
    • LXR beta antibody
    • LXRB antibody
    • NER antibody
    • NER I antibody
    • NER1 antibody
    • NR1H 2 antibody
    • NR1H2 antibody
    • NR1H2_HUMAN antibody
    • Nuclear orphan receptor LXR beta antibody
    • Nuclear receptor NER antibody
    • Nuclear receptor subfamily 1 group H member 2 antibody
    • OR-1 antibody
    • Oxysterols receptor LXR-beta antibody
    • RIP15 antibody
    • Steroid hormone nuclear receptor NER antibody
    • Ubiquitously-expressed nuclear receptor antibody
    • UNR antibody
    see all


  • Anti-LXR beta/NER antibody (ab24361) at 1 µg/ml + Human Bone Marrow lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 51 kDa
    Observed band size: 60,80 kDa (why is the actual band size different from the predicted?)

    Exposure time: 1 hour
  • ab24361 at 3µg/ml staining LXR beta/NER in human spleen tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections). Tissue underwent antigen retrieval in steam in citrate buffer pH 6.0. AP staining procedure was used for detection.


This product has been referenced in:
  • Courtaut F  et al. Liver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRß subcellular localization. Oncotarget 6:26651-62 (2015). IHC . Read more (PubMed: 26450852) »

See 1 Publication for this product

Customer reviews and Q&As

Merci de nous avoir contactés.

Garantie sur les produits Abcam: nos produitssont garantis pour fonctionner tels qu'ils sont décrits sur la fiche technique (garantie Abpromise). Nous pouvons donc toujours résoudre un probl...

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Thank you foryour message.

I can confirm that you will need to dilute the antibody before you use it in an experiment.

We recommend to only dilute the amount of antibody you need. The rest should be stored undiluted as recommended...

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Thank you for your message

As stated on the datasheet, the vial size is 100 µg. This is the only size we provide for this product.

As my customer service colleague has previously discussed with you, unfortunately, Abcam does...

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Thank you for your enquiry and your interest in our products.

We have several antibodies against LXR beta (ab24361, ab56237, ab58089, ab58092, ab76983, ab106473) . The tested application/species/unit size can be found on the on-line product d...

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Thank you for your email. For both of these antibodies, ab3585 and ab24361, they have only so been tested for cross-reactivity with human and have not yet been tested in other species. Ab24361 is predicted to react with Mouse (85% identity with immunog...

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