Overview

  • Product name

    LY 225910, CCK2 receptor antagonist
  • Description

    Potent, selective CCK2 receptor antagonist
  • Biological description

    Potent, selective CCK2 receptor antagonist (IC50 = 9.3 nM). Shows anxiolytic effects in vivo.
  • Purity

    > 99%
  • CAS Number

    133040-77-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Hajizadeh Moghaddam A  et al. Anxiogenic effect of CCK8s in the ventral hippocampus of rats: possible involvement of GABA(A) receptors. Pharmacol Rep 64:45-53 (2012). Read more (PubMed: 22580519) »
  • Bertoglio LJ  et al. Cholecystokinin-2 receptors modulate freezing and escape behaviors evoked by the electrical stimulation of the rat dorsolateral periaqueductal gray. Brain Res 1156:133-8 (2007). Read more (PubMed: 17498673) »
  • Ballaz SJ  et al. The CCK-system mediates adaptation to novelty-induced stress in the rat: a pharmacological evidence. Neurosci Lett 428:27-32 (2007). Read more (PubMed: 17950531) »
See 1 Publication for this product

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