Key features and details
- Negative control for LY 294002 (ab120243)
- CAS Number: 154447-38-8
- Purity: > 98%
- Soluble in DMSO to 100 mM, in ethanol to 100 mM and in 1 eq. HCl to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameLY 303511 dihydrochloride, Negative control for LY 294002
DescriptionNegative control for LY 294002 (ab120243)
Negative control for LY 294002 (ab120243). PI3K inhibitory activity. Inhibits voltage-gated Kv channel activity (IC50 = 64.6 μM). Various pharmacological effects including inhibition of LPS-stimulated FPR1 expression and induction of H2O2 production.
Chemical name8-Phenyl-2-(1-piperazinyl)-4H-1-benzopyran-4-one dihydrochloride
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM, in ethanol to 100 mM and in 1 eq. HCl to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120956 has been referenced in 1 publication.
- Li H et al. Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways. Free Radic Biol Med 120:228-238 (2018). PubMed: 29559323