Key features and details
- Rat monoclonal [HK1.4] to Ly6c (FITC)
- Suitable for: Flow Cyt, Cellular Activation, IHC-Fr
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2c
Product nameAnti-Ly6c antibody [HK1.4] (FITC)
See all Ly6c primary antibodies
DescriptionRat monoclonal [HK1.4] to Ly6c (FITC)
ConjugationFITC. Ex: 493nm, Em: 528nm
Specificityab25025 recognises murine Ly-6C.
Tested applicationsSuitable for: Flow Cyt, Cellular Activation, IHC-Frmore details
Species reactivityReacts with: Mouse
The details of the immunogen for this antibody are not available.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.1% Sodium azide
Concentration information loading...
Light chain typekappa
Our Abpromise guarantee covers the use of ab25025 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 1µg for 106 cells.
ab114134 - Rat monoclonal IgG2c, is suitable for use as an isotype control with this antibody.
|Cellular Activation||Use at an assay dependent concentration. In vitro activation of T lymphocytes.|
|IHC-Fr||Use at an assay dependent concentration.|
RelevanceLy6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T cell subsets. Mice with the Ly6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly6C+ and CD8+Ly6C+ cells, while Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly6C+ lymphocytes.
Cellular localizationCell membrane; Lipid-anchor, GPI-anchor.
- Ly 6c antibody
- Ly6c protein antibody
- Ly6c1 antibody
ab25025 has been referenced in 1 publication.
- Deshmukh US et al. Inflammatory stimuli accelerate Sjögren's syndrome-like disease in (NZB x NZW)F1 mice. Arthritis Rheum 58:1318-23 (2008). PubMed: 18438852