Overview

  • Product name

    Anti-Ly6g antibody [1A8] (FITC)
    See all Ly6g primary antibodies
  • Description

    Rat monoclonal [1A8] to Ly6g (FITC)
  • Host species

    Rat
  • Conjugation

    FITC. Ex: 493nm, Em: 528nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • C57Bl/6 bone marrow cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab210203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Suggested use 0.25 μg.

Target

  • Relevance

    Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells.
  • Cellular localization

    Attached to the membrane by a GPI-anchor.
  • Database links

  • Alternative names

    • Gr-1 antibody
    • Gr1 antibody
    • Ly-6G.1 antibody
    • Ly6G antibody
    • Lymphocyte antigen 6 complex locus G antibody
    • Lymphocyte antigen 6G antibody
    see all

Images

  • Flow cytometric analysis of C57Bl/6 mouse bone marrow cells labeling Ly6g with ab210203 at 0.25 µg (solid line) or FITC rat IgG2a isotype control at 0.25 µg (dashed line).

References

This product has been referenced in:

  • Wu M  et al. MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma. Nat Commun 9:4777 (2018). Read more (PubMed: 30429468) »
See 1 Publication for this product

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