Anti-Ly6g antibody [1A8] - Low endotoxin, Azide free (ab210204)

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Key features and details

  • Rat monoclonal [1A8] to Ly6g - Low endotoxin, Azide free
  • Reacts with: Mouse
  • Isotype: IgG2a

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Overview

  • Product name

    Anti-Ly6g antibody [1A8] - Low endotoxin, Azide free
    See all Ly6g primary antibodies

  • Description

    Rat monoclonal [1A8] to Ly6g - Low endotoxin, Azide free

  • Host species

    Rat

  • Species reactivity

    Reacts with: Mouse

  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes

    Endotoxin Level: Less than or equal to 0.01 EU/μg, as determined by the LaL assay.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

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Properties

Target

  • Relevance

    Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells.

  • Cellular localization

    Attached to the membrane by a GPI-anchor.

  • Database links

    • Alternative names

      • Gr-1 antibody
      • Gr1 antibody
      • Ly-6G.1 antibody
      • Ly6G antibody
      • Lymphocyte antigen 6 complex locus G antibody
      • Lymphocyte antigen 6G antibody
      see all

    References (7)

    Publishing research using ab210204? Please let us know so that we can cite the reference in this datasheet.

    ab210204 has been referenced in 7 publications.

    • Dhanesha N  et al. Cellular fibronectin promotes deep vein thrombosis in diet-induced obese mice. J Thromb Haemost 19:814-821 (2021). PubMed: 33300307
    • Liang Y  et al. Role of neutrophil chemoattractant CXCL5 in SARS-CoV-2 infection-induced lung inflammatory innate immune response in an in vivo hACE2 transfection mouse model. Zool Res 41:621-631 (2020). PubMed: 33045777
    • Zhou J  et al. Mannan-binding lectin deficiency exacerbates sterile liver injury in mice through enhancing hepatic neutrophil recruitment. J Leukoc Biol 105:177-186 (2019). PubMed: 30351498
    • Winstel V  et al. Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection. mBio 10:N/A (2019). PubMed: 31719177
    • Wen G  et al. Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis. J Am Heart Assoc 7:N/A (2018). PubMed: 29437605
    • Verbiest T  et al. Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis. Leukemia 32:1435-1444 (2018). PubMed: 29556020
    • Feng Z  et al. Ly6G+ neutrophil-derived miR-223 inhibits the NLRP3 inflammasome in mitochondrial DAMP-induced acute lung injury. Cell Death Dis 8:e3170 (2017). PubMed: 29144508

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