Overview

  • Product name

    Anti-Lymphocytes+Langerhans cells antibody [MS gp2]
  • Description

    Mouse monoclonal [MS gp2] to Lymphocytes+Langerhans cells
  • Host species

    Mouse
  • Specificity

    ab27922 recognises an antigen on the majority of T and B lymphocytes and thymocytes, and it reacts strongly with epidermal Langerhans cells, giving a superior profile than anti MHC Class II antibodies on these cells. The antigen recognised by ab27922 is not expressed by germinal centre cells of the lymph node.
  • Tested applications

    Suitable for: IHC-Frmore details
    Unsuitable for: ELISA,Flow Cyt,IHC-P,IHC-R,Inhibition,IP,RIA or WB
  • Species reactivity

    Reacts with: Guinea pig
  • Immunogen

    Tissue/ cell preparation: Nylon wool adherent B cells (Guinea pig)

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    MS gp2
  • Myeloma

    NS1
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab27922 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr
  • Application notes

    IHC-Fr: Use at an assay dependent dilution.

    Is unsuitable for ELISA, FACS, IHC-P, IHC-R, IP, Inhib, RIA or WB. Does not functionally inhibit lymphocyte adherence to high endothelial venules in vitro.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance

      Lymphocytes have receptors for antigen and confer specificity on an immune response. Lymphocytes express receptors with varying affinity for the antigen in question. Langerhans Cells are present in the skin and process efficiently antigen but cannot present it to T cells. Langerhans cells have been shown to pick up antigen in skin and carry it via afferent lymphatic vessels to lymph nodes.

    References

    This product has been referenced in:

    • Healey DG  et al. An antigenic determinant common to lymphocytes and Langerhans cells of the guinea pig. Int Arch Allergy Appl Immunol 82:120-4 (1987). Read more (PubMed: 2433227) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab27922.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Sign up