Recombinant
RabMAb

Recombinant Anti-LYPD3 antibody [SP208], prediluted (ab228289)

Overview

  • Product name

    Anti-LYPD3 antibody [SP208], prediluted
    See all LYPD3 primary antibodies
  • Description

    Rabbit monoclonal [SP208] to LYPD3, prediluted
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human LYPD3 aa 200-300 (internal sequence). The exact sequence is proprietary.
    Database link: O95274

  • Positive control

    • IHC-P: Human skin, esophagus, tonsil, bladder, cervix, breast ductal cell carcinoma, skin squamous cell carcinoma and cervical squamous cell carcinoma tissues.

Properties

  • Form

    Prediluted
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Do Not Freeze.
  • Storage buffer

    pH: 7.6
    Preservative: 0.1% Sodium azide
    Constituents: Tris buffered saline, 1% BSA
  • Concentration information loading...
  • Purity

    Protein A/G purified
  • Purification notes

    Purified from TCS by protein A/G.
  • Clonality

    Monoclonal
  • Clone number

    SP208
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab228289 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1.

Ready to use. Perform heat mediated antigen retrieval by boiling tissue section in citrate buffer for 10 minutes followed by cooling at room temperature for 20 minutes. Incubate with primary antibody for 10 minutes at room temperature.

Target

  • Function

    Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.
  • Tissue specificity

    Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers.
  • Sequence similarities

    Contains 2 UPAR/Ly6 domains.
  • Post-translational
    modifications

    N-glycosylated and O-glycosylated.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 2310061G07Rik antibody
    • C4.4A antibody
    • GPI-anchored metastasis-associated protein C4.4A homolog antibody
    • GPI-anchored metastasis-associated protein homolog antibody
    • Ly6/PLAUR domain-containing protein 3 antibody
    • Lypd3 antibody
    • LYPD3_HUMAN antibody
    • Matrigel-induced gene C4 protein antibody
    • MIG-C4 antibody
    • SHINC3 antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human cervical squamous cell carcinoma tissue stained for LYPD3 using ab2288289 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human skin squamous cell carcinoma tissue stained for LYPD3 using ab2288289 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human breast ductal cell carcinoma tissue stained for LYPD3 using ab2288289 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human cervix tissue stained for LYPD3 using ab2288289 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human bladder tissue stained for LYPD3 using ab2288289 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human tonsil tissue stained for LYPD3 using ab2288289 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human esophagus tissue stained for LYPD3 using ab2288289 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human skin tissue stained for LYPD3 using ab2288289 in immunohistochemical analysis.

References

ab228289 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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