lyso-Ceramide trihexoside, metabolite of globotriaosylsphingosine (ab143966)

Overview

  • Product name

    lyso-Ceramide trihexoside, metabolite of globotriaosylsphingosine
  • Description

    Deacylated metabolite of globotriaosylsphingosine
  • Biological description

    Deacylated metabolite of globotriaosylsphingosine. Blood biomarker in Fabry nephropathy. Shiga toxin receptor. Possible use as an internal standard in glycosphingolipid studies.
  • Purity

    > 98%
  • CAS Number

    126550-86-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2R,3R,4S,5R,6R)-2-[(2R,3R,4R,5R,6S)-6-[(2R,3S,4R,5R,6R)-6-[(E,2S,3R)-2-Amino-3-hydroxyoctadec-4-enoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
  • Molecular weight

    785.92
  • Molecular formula

    C36H67NO17
  • PubChem identifier

    6449939
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O[C@@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)O)O)O)O)O)N)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Lukas J  et al. Functional characterisation of alpha-galactosidase a mutations as a basis for a new classification system in fabry disease. PLoS Genet 9:e1003632 (2013). Read more (PubMed: 23935525) »
  • Sanchez-Niño MD  et al. Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy. Nephrol Dial Transplant 26:1797-802 (2011). Read more (PubMed: 20504837) »
  • Cooling LL  et al. Shiga toxin binds human platelets via globotriaosylceramide (Pk antigen) and a novel platelet glycosphingolipid. Infect Immun 66:4355-66 (1998). Read more (PubMed: 9712788) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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