Product namelyso-Lactosylceramide, Glycosphingolipid precursor
Biological descriptionGlycosphingolipid precursor. Lipid secondary messenger and possible PKC activator. For use in inflammatory and lipid signaling studies and as standard. Possibly active in vitro.
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Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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This product has been referenced in:
- Johnson B et al. Analysis of lyso-globotriaosylsphingosine in dried blood spots. Ann Lab Med 33:274-8 (2013). Read more (PubMed: 23826564) »
- Won JS et al. Lactosylceramide: a lipid second messenger in neuroinflammatory disease. J Neurochem 103 Suppl 1:180-91 (2007). Read more (PubMed: 17986153) »
- Marí M et al. Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis. J Clin Invest 113:895-904 (2004). Read more (PubMed: 15067322) »