lyso-Monosialoganglioside GM1 ammonium salt, Acidic glycosphingolipid (ab143965)

Overview

  • Product name

    lyso-Monosialoganglioside GM1 ammonium salt, Acidic glycosphingolipid
  • Description

    Acidic glycosphingolipid
  • Biological description

    Acidic glycosphingolipid. Component of lipid rafts. Role in neurogenesis. For use in variety of signal transduction processes and as standard. Possible in vivo activity.
  • Purity

    > 98%
  • CAS Number

    171483-40-2
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    1297.39
  • Molecular formula

    C55H97N3O30.NH3
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    N.CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO[C@@H]5OC(CO)[C@@H](O[C@@H]4OC(CO)[C@H](O[C@@H]2OC(CO)[C@H](O)C(O[C@@H]1OC(CO)[C@H](O)C(O)[C@@H]1O)[C@@H]2NC(C)=O)C(O[C@@]3(CC(O)[C@@H](NC(C)=O)C(O3)[C@H](O)[C@H](O)CO)C(=O)O)[C@@H]4O)[C@H](O)C5O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Ichikawa N  et al. Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth. J Cell Sci 122:289-99 (2009). Read more (PubMed: 19118221) »
  • Garofalo L & Cuello AC Nerve growth factor and the monosialoganglioside GM1: analogous and different in vivo effects on biochemical, morphological, and behavioral parameters of adult cortically lesioned rats. Exp Neurol 125:195-217 (1994). Read more (PubMed: 8313938) »
  • Skaper SD & Leon A Monosialogangliosides, neuroprotection, and neuronal repair processes. J Neurotrauma 9 Suppl 2:S507-16 (1992). Read more (PubMed: 1613810) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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