Overview

  • Product name

    Lysolipin I, antibiotic agent
  • Description

    Broad spectrum antibiotic agent
  • Biological description

    Broad spectrum antibiotic agent. Shows antibacterial effects against both Gram-negative and Gram-positive bacteria. Induces bacterial cell wall lysis. Interferes with biosynthesis of the bacterial cell wall.
  • Purity

    > 98%
  • CAS Number

    59113-57-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (8aα,9β,11β,12β)-(-)-3-Chloro-8a,11,12,13-tetrahydro-11,15,16-trihydroxy-4,9,12-trimethoxy-13-methyl-9H-xantheno(4',3',2':4,5)(1,3)benzodioxino(7,6-g)isoquinoline-14,17-dione
  • Molecular weight

    597.95
  • Molecular formula

    C29H24ClNO11
  • PubChem identifier

    5492139
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN1[C@@H]([C@@H](C2=C(C1=O)C(=C3C(=C2)[C@@H]([C@H]4C5=C(C6=C(C(=C53)O)C(=O)C7=C(O6)C(=C(C=C7)Cl)OC)OCO4)OC)O)O)OC
  • Source

    Streptomyces violaceoniger

  • Research areas

References

This product has been referenced in:

  • Lopez P  et al. Isolation of the lysolipin gene cluster of Streptomyces tendae Tü 4042. Gene 461:5-14 (2010). Read more (PubMed: 20399259) »
  • Dobler M & Keller-Schierlein W Metabolites of microorganisms. 162nd Communication. The crystal and molecular structure of lysolipin I. Helv Chim Acta 60:178-85 (1977). Read more (PubMed: 838594) »
  • Drautz H  et al. [Metabolic products of microorganisms, 149. Lysolipin I, a new antibiotic from streptomyces violaceoniger (author's transl)]. Arch Microbiol 106:175-90 (1975). Read more (PubMed: 814871) »

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