Product nameLysophosphatidic acid sodium salt, autophagy inhibitor
- 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid, sodium salt
- 1-Oleoyl-lysophosphatidic acid sodium salt
- LPA sodium salt
Endogenous agonist of the Lysophosphatidic acid (LPA) receptors. Induces cellular functions such as cell proliferation and migration, and ICAM-1, IL-8 and MCP-1 expression. Inhibits autophagy in cells under starvation conditions by inhibiting autophagosome formation.
1-O-9Z-Octadecenoyl-sn-glyceryl-3-phosphoric acid sodium salt
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in water to 20 mM (with warming)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146430 has been referenced in 1 publication.
- Chabowski DS et al. Lysophosphatidic acid acts on LPA1 receptor to increase H2 O2 during flow-induced dilation in human adipose arterioles. Br J Pharmacol 175:4266-4280 (2018). PubMed: 30153326