Validated using a knockout cell line

Recombinant Anti-M6PR (cation independent) antibody [EPR6599] - Lysosome Membrane Marker (ab124767)

Publishing research using ab124767? Please let us know so that we can cite the reference in this datasheet.

ab124767 has been referenced in 24 publications.

  • Cui Y  et al. A role of GCC88 in the retrograde transport of CI-M6PR and the maintenance of lysosomal activity. Cell Biol Int N/A:N/A (2019). PubMed: 30791178
  • Han SO  et al. Salmeterol with Liver Depot Gene Therapy Enhances the Skeletal Muscle Response in Murine Pompe Disease. Hum Gene Ther N/A:N/A (2019). PubMed: 30803275
  • Appu AP  et al. Cln3-mutations underlying juvenile neuronal ceroid lipofuscinosis cause significantly reduced levels of Palmitoyl-protein thioesterases-1 (Ppt1)-protein and Ppt1-enzyme activity in the lysosome. J Inherit Metab Dis N/A:N/A (2019). PubMed: 31025705
  • Huang CY  et al. Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure. Data Brief 16:521-526 (2018). PubMed: 29270451
  • Uemura T  et al. GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth. Sci Rep 8:1368 (2018). PubMed: 29358589
  • Huang CY  et al. Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy. Int J Cardiol 257:283-290 (2018). WB . PubMed: 29180262
  • Koeberl DD  et al. Correction of Biochemical Abnormalities and Improved Muscle Function in a Phase I/II Clinical Trial of Clenbuterol in Pompe Disease. Mol Ther 26:2304-2314 (2018). PubMed: 30025991
  • Jimenez-Orgaz A  et al. Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy. EMBO J 37:235-254 (2018). PubMed: 29158324
  • Nie J  et al. Dendrobium nobile Lindl. Alkaloids Decreases the Level of Intracellular ß-Amyloid by Improving Impaired Autolysosomal Proteolysis in APP/PS1 Mice. Front Pharmacol 9:1479 (2018). PubMed: 30618767
  • Pellegrini L  et al. Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice. Hum Mol Genet 27:3257-3271 (2018). PubMed: 29917075
  • Tammineni P  et al. Impaired axonal retrograde trafficking of the retromer complex augments lysosomal deficits in Alzheimer's disease neurons. Hum Mol Genet 26:4352-4366 (2017). PubMed: 28973312
  • Court H  et al. Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT. J Cell Biol 216:4165-4182 (2017). PubMed: 29051265
  • Huang CY  et al. p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure. Cell Death Dis 8:e2990 (2017). PubMed: 28796250
  • Duclos CM  et al. Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling. Cell Death Discov 3:16100 (2017). Human . PubMed: 28179995
  • Elwell CA  et al. Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction. Elife 6:N/A (2017). PubMed: 28252385
  • Rofe AP  et al. The Rhodococcus equi virulence protein VapA disrupts endolysosome function and stimulates lysosome biogenesis. Microbiologyopen 6:N/A (2017). PubMed: 27762083
  • Kvainickas A  et al. Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport. J Cell Biol 216:3677-3693 (2017). WB . PubMed: 28935632
  • McMillan KJ  et al. Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins. J Cell Biol 214:389-99 (2016). PubMed: 27528657
  • Huang PC  et al. Anthocyanin Attenuates Doxorubicin-Induced Cardiomyotoxicity via Estrogen Receptor-a/ß and Stabilizes HSF1 to Inhibit the IGF-IIR Apoptotic Pathway. Int J Mol Sci 17:N/A (2016). PubMed: 27657062
  • Bracamontes CG  et al. The serum protein profile of early parity which induces protection against breast cancer. Oncotarget 7:82538-82553 (2016). WB ; Human . PubMed: 27769065
  • Sato S  et al. Lysosomal Storage of Subunit c of Mitochondrial ATP Synthase in Brain-Specific Atp13a2-Deficient Mice. Am J Pathol 186:3074-3082 (2016). PubMed: 27770614
  • Ju X  et al. Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture. J Virol 89:10347-58 (2015). PubMed: 26246576
  • Fuse A  et al. VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process. FEBS Lett 589:1430-6 (2015). PubMed: 25937119
  • Miura E  et al. VPS35 dysfunction impairs lysosomal degradation of a-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease. Neurobiol Dis 71:1-13 (2014). PubMed: 25107340

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