M871, Galanin GAL2 receptor antagonist (ab141159)
- Datasheet
- References
Overview
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Product name
M871, Galanin GAL2 receptor antagonist -
Description
Selective galanin GAL2 receptor antagonist -
Biological description
Selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM at GAL2 and GAL1 receptors, respectively). Blocks pronociceptive effects of GAL2 agonists including AR-M1896. Active in vivo. -
CAS Number
908844-75-7 -
Chemical structure
Properties
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Molecular weight
2287.64 -
Molecular formula
C108H163N27O28 -
Sequence
WTLNSAGYLLGPEHPPPALALA (Modifications: C-terminal amide) -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
References
This product has been referenced in:
- Jimenez-Andrade JM et al. Activation of peripheral galanin receptors: differential effects on nociception. Pharmacol Biochem Behav 85:273-80 (2006). Read more (PubMed: 16996122) »
