Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab122889)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-Macrophage Inflammatory Protein 3 alpha antibody
See all Macrophage Inflammatory Protein 3 alpha primary antibodies -
Description
Goat polyclonal to Macrophage Inflammatory Protein 3 alpha -
Host species
Goat -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Cow, Pig
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Immunogen
Synthetic peptide conjugated to KLH, from internal sequence amino acids of Human Macrophage Inflammatory Protein 3 alpha.
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Positive control
- Human Liver tissue.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab122889 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 6.13 µg/ml. |
Target
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Function
Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. -
Tissue specificity
Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon. -
Sequence similarities
Belongs to the intercrine beta (chemokine CC) family. -
Post-translational
modificationsC-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 281666 Cow
- Entrez Gene: 6364 Human
- Entrez Gene: 553951 Pig
- Omim: 601960 Human
- SwissProt: Q8SQB1 Cow
- SwissProt: P78556 Human
- Unigene: 75498 Human
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Alternative names
- Beta-chemokine exodus-1 antibody
- C C motif chemokine ligand 20 antibody
- C-C motif chemokine 20 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab122889)ab122889, at 6.13 µg/ml, staining Macrophage Inflammatory Protein 3 alpha in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.
Protocols
Datasheets and documents
References
ab122889 has not yet been referenced specifically in any publications.
