Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab122889)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab122889)

    Key features and details

    • Goat polyclonal to Macrophage Inflammatory Protein 3 alpha
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-Macrophage Inflammatory Protein 3 alpha antibody
      See all Macrophage Inflammatory Protein 3 alpha primary antibodies

    • Description

      Goat polyclonal to Macrophage Inflammatory Protein 3 alpha

    • Host species

      Goat

    • Tested Applications & Species

      Application Species
      IHC-P
      Human
      See all applications and species data

    • Immunogen

      Synthetic peptide conjugated to KLH, from internal sequence amino acids of Human Macrophage Inflammatory Protein 3 alpha.

    • Positive control

      • Human Liver tissue.

    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

      One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

      Learn more here.

    Properties

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab122889 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    IHC-P
    Human
    All applications
    Cow
    Pig
    Application Abreviews Notes
    IHC-P
    Use a concentration of 6.13 µg/ml.
    Notes
    IHC-P
    Use a concentration of 6.13 µg/ml.

    Target

    • Function

      Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.

    • Tissue specificity

      Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.

    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.

    • Post-translational
      modifications

      C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

    • Cellular localization

      Secreted.
    • Information by UniProt

    • Database links

      • Alternative names

        • Beta chemokine exodus 1 antibody
        • Beta-chemokine exodus-1 antibody
        • C C motif chemokine ligand 20 antibody
        • C-C motif chemokine 20 antibody
        • CC chemokine LARC antibody
        • Ccl20 antibody
        • CCL20(2-70) antibody
        • CCL20_HUMAN antibody
        • Chemokine (C C motif) ligand 20 antibody
        • Chemokine C-C motif chemokine 20 antibody
        • Chemokine CC motif ligand 20 antibody
        • CKb4 antibody
        • Exodus 1 antibody
        • Exodus antibody
        • LARC antibody
        • Liver and activation regulated chemokine antibody
        • Liver and activation-regulated chemokine antibody
        • Macrophage inflammatory protein 3 alpha antibody
        • MIP 3 alpha antibody
        • MIP 3A antibody
        • MIP-3-alpha antibody
        • MIP-3a antibody
        • MIP3 alpha antibody
        • MIP3A antibody
        • SCYA20 antibody
        • Small inducible cytokine A20 antibody
        • Small inducible cytokine subfamily A (Cys Cys) member 20 antibody
        • Small-inducible cytokine A20 antibody
        • ST38 antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab122889)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab122889)
        ab122889, at 6.13 µg/ml, staining Macrophage Inflammatory Protein 3 alpha in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.

      References (0)

      Publishing research using ab122889? Please let us know so that we can cite the reference in this datasheet.

      ab122889 has not yet been referenced specifically in any publications.

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