Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab122889)
- Datasheet
- Specific References
- Protocols
Overview
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Product nameAnti-Macrophage Inflammatory Protein 3 alpha antibody
See all Macrophage Inflammatory Protein 3 alpha primary antibodies -
DescriptionGoat polyclonal to Macrophage Inflammatory Protein 3 alpha
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Host speciesGoat
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Tested applicationsSuitable for: IHC-Pmore details
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Species reactivityReacts with: Human
Predicted to work with: Cow, Pig
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Immunogen
Synthetic peptide conjugated to KLH, from internal sequence amino acids of Human Macrophage Inflammatory Protein 3 alpha.
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Positive control
- Human Liver tissue.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
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Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
PurityProtein G purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
Applications
Our Abpromise guarantee covers the use of ab122889 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 6.13 µg/ml. |
Target
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FunctionChemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
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Tissue specificityExpressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
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Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
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Post-translational
modificationsC-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes. -
Cellular localizationSecreted.
- Information by UniProt
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Database links
- Entrez Gene: 281666 Cow
- Entrez Gene: 6364 Human
- Entrez Gene: 553951 Pig
- Omim: 601960 Human
- SwissProt: Q8SQB1 Cow
- SwissProt: P78556 Human
- Unigene: 75498 Human
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Alternative names
- Beta-chemokine exodus-1 antibody
- C C motif chemokine ligand 20 antibody
- C-C motif chemokine 20 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab122889)ab122889, at 6.13 µg/ml, staining Macrophage Inflammatory Protein 3 alpha in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.
Protocols
References
ab122889 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"