Recombinant
RabMAb

Anti-Macrophage Inflammatory Protein 3 antibody [EPR11364] (ab170958)

Overview

  • Product name
    Anti-Macrophage Inflammatory Protein 3 antibody [EPR11364]
    See all Macrophage Inflammatory Protein 3 primary antibodies
  • Description
    Rabbit monoclonal [EPR11364] to Macrophage Inflammatory Protein 3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human Macrophage Inflammatory Protein 3 aa 1-100. The exact sequence is proprietary.
    Database link: P55773

  • Positive control
    • Human Macrophage Inflammatory Protein 3 recombinant protein, HepG2 cells.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab170958 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 13 kDa.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function
      Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.
    • Tissue specificity
      High levels in adult lung, liver, skeletal muscle and pancreas. Moderate levels in fetal liver, adult bone marrow and placenta. The short form is the major species and the longer form was detected only in very low abundance. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are found in high levels in synovial fluids from rheumatoid patients.
    • Sequence similarities
      Belongs to the intercrine beta (chemokine CC) family.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • C C motif chemokine ligand 23 antibody
      • C-C motif chemokine 23 antibody
      • C6 beta chemokine antibody
      • CCL 23 antibody
      • CCL23 antibody
      • CCL23(30-99) antibody
      • CCL23_HUMAN antibody
      • Chemokine (C C motif) ligand 23 antibody
      • Chemokine CC motif ligand 23 antibody
      • ck beta 8 antibody
      • CK-beta-8 antibody
      • CKB 8 antibody
      • CKB-8 antibody
      • Ckb-8-1 antibody
      • CKB8 antibody
      • Hmrp-2a antibody
      • Macrophage inflammatory protein 3 antibody
      • MIP 3 antibody
      • MIP-3 antibody
      • MIP3 antibody
      • MPIF 1 antibody
      • MPIF-1 antibody
      • MPIF1 antibody
      • Myeloid progenitor inhibitory factor 1 antibody
      • OTTHUMP00000163948 antibody
      • SCYA 23 antibody
      • SCYA23 antibody
      • Small inducible cytokine A 23 antibody
      • Small inducible cytokine subfamily A (Cys-Cys), member 23 antibody
      • Small inducible cytokine subfamily A, member 23 antibody
      • Small-inducible cytokine A23 antibody
      see all

    Images

    • Anti-Macrophage Inflammatory Protein 3 antibody [EPR11364] (ab170958) at 1/1000 dilution + Human Macrophage Inflammatory Protein 3 recombinant protein (5ng)

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Developed using the ECL technique.

      Predicted band size: 13 kDa

    • Immunofluorescence analysis of HepG2 cells, labeling Macrophage Inflammatory Protein 3 (red) using ab170958 at a 1/100 dilution. DAPI nuclear staining (blue).

    References

    ab170958 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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