Product nameAnti-Macrophage Scavenger Receptor I antibody
See all Macrophage Scavenger Receptor I primary antibodies
DescriptionRabbit polyclonal to Macrophage Scavenger Receptor I
Tested applicationsSuitable for: WB, ICC/IF, IHC-P, IHC-Frmore details
Species reactivityReacts with: Rat, Cow, Cat, Human, Monkey
Synthetic peptide, corresponding to a region within amino acids 300-400 of Human Macrophage Scavenger Receptor I (UniProt P21757).
- Hela cells; Human liver lysate
Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.
Storage bufferPreservative: 0.1% Sodium azide
Constituents: 69% PBS, 30% Glycerol
Concentration information loading...
PurityProtein A purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
Our Abpromise guarantee covers the use of ab123946 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.5 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).|
|ICC/IF||1/50 - 1/200.|
|IHC-P||Use at an assay dependent concentration.|
|IHC-Fr||Use at an assay dependent concentration.|
FunctionMembrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize actetylated LDL.
Tissue specificityIsoform I, isoform II and isoform III are expressed in monocyte-derived macrophages.
Sequence similaritiesContains 1 collagen-like domain.
Contains 1 SRCR domain.
- Information by UniProt
- CD204 antibody
- CD204 antigen antibody
- CD24 antibody
Anti-Macrophage Scavenger Receptor I antibody (ab123946) at 0.5 µg/ml + Human liver lysate
Predicted band size: 50 kDa
Observed band size: 50 kDa
ab123946, at a 1/50 dilution, staining Macrophage Scavenger Receptor I (green) in Hela cells by Immunofluorescence. Nuclei (blue) are counterstained using Hoechst 33258.
This product has been referenced in:
- Chang TT et al. Fucosyl-Agalactosyl IgG1 Induces Cholangiocarcinoma Metastasis and Early Recurrence by Activating Tumor-Associated Macrophage. Cancers (Basel) 10:N/A (2018). Read more (PubMed: 30469416) »
- Pasterk L et al. Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression. Sci Rep 6:22104 (2016). Read more (PubMed: 26905525) »