Product nameAnti-Macrophage Scavenger Receptor I/SR-A antibody
See all Macrophage Scavenger Receptor I/SR-A primary antibodies
DescriptionGoat polyclonal to Macrophage Scavenger Receptor I/SR-A
SpecificityRecognises the 75 kDa membrane glycoprotein human macrophage scavenger receptor (MSR) type 1. MSR1 has been shown to be expressed on microglia and mato cells of the brain but not astrocytes or neurons.
Tested applicationsSuitable for: ELISA, IHC-P, WBmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human Macrophage Scavenger Receptor I/SR-A aa 325-342.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
Our Abpromise guarantee covers the use of ab6417 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent dilution.|
|IHC-P||Use at an assay dependent dilution.|
FunctionMembrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize actetylated LDL.
Tissue specificityIsoform I, isoform II and isoform III are expressed in monocyte-derived macrophages.
Sequence similaritiesContains 1 collagen-like domain.
Contains 1 SRCR domain.
- Information by UniProt
- CD204 antibody
- CD204 antigen antibody
- CD24 antibody
This product has been referenced in:
- Khan A et al. Mesenchymal stem cells internalize Mycobacterium tuberculosis through scavenger receptors and restrict bacterial growth through autophagy. Sci Rep 7:15010 (2017). Read more (PubMed: 29118429) »
- Maleszewski J et al. Robust immunohistochemical staining of several classes of proteins in tissues subjected to autolysis. J Histochem Cytochem 55:597-606 (2007). IHC-P ; Human . Read more (PubMed: 17312010) »