Anti-MXD4/MAD4 antibody (ab111062)
Key features and details
- Rabbit polyclonal to MXD4/MAD4
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MXD4/MAD4 antibody -
Description
Rabbit polyclonal to MXD4/MAD4 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to Human MXD4/MAD4 aa 1-100.
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Positive control
- Human brain tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49.1% PBS, 0.88% Sodium chloride
PBS (without Mg2+ and Ca2+) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab111062 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab111062 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. -
Sequence similarities
Contains 1 bHLH (basic helix-loop-helix) domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 10608 Human
- Entrez Gene: 17122 Mouse
- SwissProt: Q14582 Human
- SwissProt: Q60948 Mouse
- Unigene: 655020 Human
- Unigene: 259260 Mouse
- Unigene: 391777 Mouse
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Alternative names
- bHLHc12 antibody
- Class C basic helix loop helix protein 12 antibody
- Class C basic helix-loop-helix protein 12 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab111062 has not yet been referenced specifically in any publications.