Overview

  • Product name
    Anti-MAGE 1 antibody
    See all MAGE 1 primary antibodies
  • Description
    Rabbit polyclonal to MAGE 1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Positive control
    • Testis and Melanoma

Properties

Applications

Our Abpromise guarantee covers the use of ab16031 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF
IHC-P
  • Application notes
    IHC-P: 1/200 for 10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at RT for 20 minutes.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • Function
      May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
    • Tissue specificity
      Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
    • Sequence similarities
      Contains 1 MAGE domain.
    • Cellular localization
      Cytoplasm. Nucleus.
    • Information by UniProt
    • Database links
      • Alternative names
        • Antigen MZ2 E antibody
        • Antigen MZ2-E antibody
        • Cancer/testis antigen 1.1 antibody
        • cancer/testis antigen family 1, member 1 antibody
        • CT1.1 antibody
        • MAGA1_HUMAN antibody
        • MAGE 1 antigen antibody
        • MAGE-1 antigen antibody
        • MAGE1 antibody
        • MAGE1A antibody
        • MAGEA1 antibody
        • Melanoma antigen 1 antibody
        • Melanoma antigen family A 1 (directs expression of antigen MZ2 E) antibody
        • Melanoma antigen family A 1 antibody
        • Melanoma antigen MAGE 1 antibody
        • Melanoma associated antigen 1 antibody
        • Melanoma associated antigen MZ2 E antibody
        • Melanoma-associated antigen 1 antibody
        • MGC9326 antibody
        see all

      References

      ab16031 has not yet been referenced specifically in any publications.

      Publishing research using ab16031? Please let us know so that we can cite the reference in this datasheet.

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