Key features and details
- Rabbit polyclonal to MAGEA1
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MAGEA1 antibody
See all MAGEA1 primary antibodies
DescriptionRabbit polyclonal to MAGEA1
Tested applicationsSuitable for: ICC/IF, IHC-Pmore details
Species reactivityReacts with: Human
Recombinant full length protein corresponding to Human MAGEA1.
- Testis and Melanoma
This product is FOR RESEARCH USE ONLY. For commercial use, please contact email@example.com.
This product was previously labelled as MAGE 1
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab16031 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionMay be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Tissue specificityExpressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
Sequence similaritiesContains 1 MAGE domain.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- Antigen MZ2 E antibody
- Antigen MZ2-E antibody
- Cancer/testis antigen 1.1 antibody
Immunofluorescence staining with Mouse monoclonal [8C10] to SCAMP1+2+3 (ab17053; red) on Human HEK cells. Cells were fixed in methanol, no antigen retrieval step was necessary. Primary antibody was incubated for 1 hour at 5µg/ml. The confocal image shows anti-SCAMP in red and nuclear counterstain in blue.
ab16031 has not yet been referenced specifically in any publications.