Overview

  • Product name

  • Description

    Rabbit polyclonal to MAG/GMA
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human MAG/GMA aa 580-625 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    ERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRV


    Database link: P20916

  • Positive control

    • IHC-P: Rat brain tissue.
  • General notes

     This product was previously labelled as MAG

Properties

Applications

Our Abpromise guarantee covers the use of ab203058 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid.
  • Sequence similarities

    Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
    Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • GMA antibody
    • MAG antibody
    • MAG_HUMAN antibody
    • Myelin associated glycoprotein antibody
    • Myelin-associated glycoprotein antibody
    • S MAG antibody
    • S-MAG antibody
    • Sialic acid binding Ig like lectin 4A antibody
    • Sialic acid binding immunoglobulin like lectin 4A antibody
    • Siglec 4a antibody
    • Siglec-4a antibody
    • SIGLEC4A antibody
    • SPG75 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded rat brain tissue, labeling MAG/GMA using ab203058 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

References

ab203058 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab203058.
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